FLUCONAZOLE FAILURE IN THE TREATMENT OF COCCIDIOIDAL MENINGITIS

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis.Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM.We conducted this study to understand risk factors for fluconazo

Abstract Background Epigenetic regulators are frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy.Results To define alterations in COCONUT REISHI DEODORANT epigenetic landscapes in breast cancers, we profiled the distri